Título: Professor Associado
E-mail: [email protected]
Lattes: http://lattes.cnpq.br/9322677300788116
Bolsa produtividade CNPq : PQ 1D
Orcid: ID 0000-0002-3682-4517 – https://orcid.org/0000-0002-3682-4517
Scopus: ID  7004219620 – https://www.scopus.com/authid/detail.uri?authorId=7004219620
Google scholar: ID a8E84tgAAAAJ – https://scholar.google.com.br/citations?user=a8E84tgAAAAJ&hl=pt-BR
Research ID: C-2878-2012 – https://publons.com/researcher/1354897/samuel-shinjo/


Line of research:

Systemic autoimmune myopathies: from bench to bedside

Summary

Systemic autoimmune myopathies (SAM), or idiopathic inflammatory myopathies, are a set of acquired muscle diseases composed of dermatomyositis, polymyositis, inclusion body myositis, antisynthetase syndrome, and immune-mediated necrotizing myopathy, among others.

Our objective is the translational integration of basic to clinical area research and vice versa, aiming to bring benefits to the community as a whole. In this context, the group presents a broad range of SAM-related activities: (a) characterization of autoantibody reactivity (myositis-specific and associated) and of serum cytokines (proinflammatory and angiogenesis) and their expression in muscle tissues; (b) drug intervention: treat-to-target (T2T) and the role of statins; (c) non-drug intervention: safety and relevance of physical exercise and non-invasive neuromodulation; (d) addressing comorbidities, especially related to cardiovascular diseases and their risk factors; (e) participation in the national and international SAM registry (Brazilian, Latin American and European: REMAS, Myonet, MexPan and AENEAS).

Activities

  • Inflammatory Myopathies Laboratory, LIM17, Rheumatology Department (FMUSP), SP
  • Inflammatory Myopathies Outpatient Clinic, Rheumatology Service (HCFMUSP), SP

Relevant articles:

  1. Misse RG, Dos Santos AM, Borges IBP, Grecco MV, Faria MSMS, Da Silva LRS, Correia BL, Kim AWS, Tanaka C, Greve JMA, Baptista AF, Shinjo SK. Impact of transcranial direct current stimulation in pain, fatigue, and health quality of life of patients with idiopathic inflammatory myopathies: A randomized, double-blind, sham-controlled crossover clinical trial. Int J Rheumatol. 2024.
  2. Saygin D, Glaubitz S, Zeng R, Bottai M, De Visser M, Dimachkie MM, Fiorentino D, Gerhardson I, Kuwana M, Miller FW, Needham M, Rider LG, Salem Y, Schlutter S, Shinjo SK, Wang G, Werth VP, Aggarwal R, Lundberg IE. Perfomance of the 2017 EULAR/ACR classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a scoping review. Clin Exp Rheumatol. 2024; 42(2):403-12.
  3. Souza LFA, Misse RG, Santos AM, Tanaka C, Greve JMA, Baptista AF, Shinjo SK. Transcranial direct current stimulation is safe and effective in autoimmune myopathies: a randomised, double-blind, sham-controlled trial. Clin Exp Rheumatol. 2023; 41(2):221-9.
  4. Pallo PAO, Shinjo SK. Different clinical phenotypes in anti-melanoma differentiation-associated protein 5-associated positive dermatomyositis. Clin Exp Rheumatol. 2023.; 41(2):394.
  5. Hoff LS, De Souza FHC, Miossi R, Shinjo SK. Long-term effects of early pulse methylprednisolone and intravenous immunoglobulin in patients with dermatomyositis and polymyositis. Rheumatology. 2022; 61(4):1579-88.

PROJETOS ORIENTADOR/ LINHA

Linha 6. SISTEMA IMUNE E AUTOIMUNE
PROJETO SAMUEL SHINJO: ESTUDO DA BANCADA AO LEITO EM MIOPATIAS INFLAMATÓRIAS IDIOPÁTICAS
PROJETO SAMUEL SHINJO: ESTUDO DA BANCADA AO LEITO EM VASCULITES SISTÊMICAS PRIMÁRIAS